Interstitial iodine-125 radiosurgery alone or in combination with microsurgery for pediatric patients with eloquently located low-grade glioma: a pilot study Peraud, A., et al. - The optimal therapeutic management of children with World Health Organization grade I and II gliomas not accessible to complete resection is poorly defined...IRS alone or in combination with microsurgery (in the case of larger tumors) is a safe, effective, and minimally invasive treatment strategy for eloquently located pediatric low-grade gliomas and deserves further prospective evaluation... Child's Nervous System, 03/14/07